Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells.

Piedrahita JA , et al.

Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.

Brecht WJ , et al.

A nontransgenic mouse model shows inducible amyloid-beta (Abeta) peptide deposition and elucidates the role of apolipoprotein E in the amyloid cascade.

Dolev I , et al.

Effect of macrophage-derived apolipoprotein E on hyperlipidemia and atherosclerosis of LDLR-deficient mice.

Shi W , et al.

A decreased expression of angiopoietin-like 3 is protective against atherosclerosis in apoE-deficient mice.

Ando Y , et al.

Loss of TGF-beta1 leads to increased neuronal cell death and microgliosis in mouse brain.

Brionne TC , et al.

Angiotensin II-accelerated atherosclerosis and aneurysm formation is attenuated in osteopontin-deficient mice.

Bruemmer D , et al.

Two Hsp70 family members expressed in atherosclerotic lesions.

Han Z , et al.

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

Huo Y , et al.

Impaired electroretinogram (ERG) response in apolipoprotein E-deficient mice.

Ong JM , et al.

Central role of RAGE-dependent neointimal expansion in arterial restenosis.

Sakaguchi T , et al.

Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation.

Wang H , et al.

Supplementation of diets with the black rice pigment fraction attenuates atherosclerotic plaque formation in apolipoprotein e deficient mice.

Xia M , et al.

Hypobetalipoproteinemic Mice with a Targeted Apolipoprotein (Apo) B-27.6-specifying Mutation. IN VIVO EVIDENCE FOR AN IMPORTANT ROLE OF AMINO ACIDS 1254-1744 OF ApoB IN LIPID TRANSPORT AND METABOLISM OF THE ApoB-CONTAINING LIPOPROTEIN.

Chen Z , et al.

Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient mice.

Guo Z , et al.

Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.

Holm TM , et al.

The ATP binding cassette transporter A1 (ABCA1) modulates the development of aortic atherosclerosis in C57BL/6 and apoE-knockout mice.

Joyce CW , et al.

LDL receptor but not apolipoprotein E deficiency increases diet-induced obesity and diabetes in mice.

Schreyer SA , et al.

Loss of Lymphotoxin-alpha but Not Tumor Necrosis Factor-alpha Reduces Atherosclerosis in Mice.

Schreyer SA , et al.

Reduction of blood pressure, plasma cholesterol, and atherosclerosis by elevated endothelial nitric oxide.

van Haperen R , et al.

Atherosclerosis in apoE knockout mice infected with multiple pathogens.

Burnett MS , et al.

The adhesion receptor CD44 promotes atherosclerosis by mediating inflammatory cell recruitment and vascular cell activation.

Cuff CA , et al.

Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice.

Fan YY , et al.

Apoprotein C-III deficiency markedly stimulates triglyceride secretion in vivo: comparison with apoprotein E.

Hirano T , et al.

Retrovirus-mediated expression of apolipoprotein A-I in the macrophage protects against atherosclerosis in vivo.

Ishiguro H , et al.

Mixed allogeneic chimerism with wild-type strains ameliorates atherosclerosis in apolipoprotein E-deficient mice.

Ishimori N , et al.

Iron overload diminishes atherosclerosis in apoE-deficient mice.

Kirk EA , et al.

Compared with saturated fatty acids, dietary monounsaturated fatty acids and carbohydrates increase atherosclerosis and VLDL cholesterol levels in LDL receptor-deficient, but not apolipoprotein E-deficient, mice.

Merkel M , et al.

Tea catechins prevent the development of atherosclerosis in apoprotein E-deficient mice.

Miura Y , et al.

Pathophysiology of apolipoprotein E deficiency in mice: relevance to apo E-related disorders in humans.

Moghadasian MH , et al.

ApoE(-/-) mice develop atherosclerosis in the absence of complement component C5.

Patel S , et al.

Impact of apoE deficiency on oxidative insults and antioxidant levels in the brain.

Ramassamy C , et al.

Effect of azithromycin on murine arteriosclerosis exacerbated by Chlamydia pneumoniae.

Rothstein NM , et al.

Targeted disruption of the class B scavenger receptor CD36 protects against atherosclerotic lesion development in mice [see comments]

Febbraio M , et al.

Age-dependent cytokine responses: trimethyltin hippocampal injury in wild-type, APOE knockout, and APOE4 mice.

Harry GJ , et al.

Role of endogenous nitric oxide in progression of atherosclerosis in apolipoprotein E-deficient mice.

Kauser K , et al.

Combined serum paraoxonase knockout/apolipoprotein E knockout mice exhibit increased lipoprotein oxidation and atherosclerosis.

Shih DM , et al.

The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes.

Davisson RL , et al.

Apolipoprotein-E deficiency results in an altered stress responsiveness in addition to an impaired spatial memory in young mice.

Zhou Y , et al.

The two-receptor model of lipoprotein clearance: tests of the hypothesis in knockout mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins.

Ishibashi S , et al.

Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E.

Zhang SH , et al.